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Genetic variations of DNA bindings of FOXA1 and co-factors in breast cancer susceptibility

Identifying transcription factors (TFs) whose DNA bindings are altered by genetic variants that regulate susceptibility genes is imperative to understand transcriptional dysregulation in disease etiology. Here, we develop a statistical framework to analyze extensive ChIP-seq and GWAS data and identi...

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Detalles Bibliográficos
Autores principales:	Wen, Wanqing, Chen, Zhishan, Bao, Jiandong, Long, Quan, Shu, Xiao-ou, Zheng, Wei, Guo, Xingyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438084/ https://www.ncbi.nlm.nih.gov/pubmed/34518541 http://dx.doi.org/10.1038/s41467-021-25670-9

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