AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation

Acute pancreatitis (AP) is a highly fatal acute inflammation and is often accompanied by multiple organ dysfunction syndrome (MODS). The liver, one of the most vulnerable extrapancreatic organs in AP, is the major organ involved in the evolution of the disease and correlates strongly with the occurr...

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Detalles Bibliográficos
Autores principales: Kong, Lijun, Zhang, Hewei, Lu, Chaosheng, Shi, Keqing, Huang, Hongjian, Zheng, Yushu, Wang, Yongqiang, Wang, Dan, Wang, Hongwei, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438129/
https://www.ncbi.nlm.nih.gov/pubmed/34531748
http://dx.doi.org/10.3389/fphar.2021.724514

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