Replication of the Mammalian Genome by Replisomes Specific for Euchromatin and Heterochromatin

Replisomes follow a schedule in which replication of DNA in euchromatin is early in S phase while sequences in heterochromatin replicate late. Impediments to DNA replication, referred to as replication stress, can stall replication forks triggering activation of the ATR kinase and downstream pathway...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Bellani, Marina A., Huang, Jing, James, Ryan C., Pokharel, Durga, Gichimu, Julia, Gali, Himabindu, Stewart, Grant, Seidman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438199/
https://www.ncbi.nlm.nih.gov/pubmed/34532320
http://dx.doi.org/10.3389/fcell.2021.729265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438199/
https://www.ncbi.nlm.nih.gov/pubmed/34532320
http://dx.doi.org/10.3389/fcell.2021.729265

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