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Replication of the Mammalian Genome by Replisomes Specific for Euchromatin and Heterochromatin
Replisomes follow a schedule in which replication of DNA in euchromatin is early in S phase while sequences in heterochromatin replicate late. Impediments to DNA replication, referred to as replication stress, can stall replication forks triggering activation of the ATR kinase and downstream pathway...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438199/ https://www.ncbi.nlm.nih.gov/pubmed/34532320 http://dx.doi.org/10.3389/fcell.2021.729265 |