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Unraveling the Thermodynamics of Ultra-tight Binding of Intrinsically Disordered Proteins
Protein interactions mediated by the intrinsically disordered proteins (IDPs) are generally associated with lower affinities compared to those between globular proteins. Here, we characterize the association between the intrinsically disordered HigA2 antitoxin and its globular target HigB2 toxin fro...
Autores principales: | Zavrtanik, Uroš, Hadži, San, Lah, Jurij |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438204/ https://www.ncbi.nlm.nih.gov/pubmed/34532345 http://dx.doi.org/10.3389/fmolb.2021.726824 |
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