High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells

Programmed death ligand 1 (PD-L1) expression on the surface of cancer cells affects the efficacy of anti-PD-1/PD-L1 immune checkpoint therapy. However, the mechanism underlying PD-L1 expression in cancer cells is not fully understood, particularly after ionizing radiation (IR). Here, we examined the...

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Detalles Bibliográficos
Autores principales: Permata, Tiara Bunga Mayang, Sato, Hiro, Gu, Wenchao, Kakoti, Sangeeta, Uchihara, Yuki, Yoshimatsu, Yukihiko, Sato, Itaru, Kato, Reona, Yamauchi, Motohiro, Suzuki, Keiji, Oike, Takahiro, Tsushima, Yoshito, Gondhowiardjo, Soehartati, Ohno, Tatsuya, Yasuhara, Takaaki, Shibata, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Fundamental Radiation Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438258/
https://www.ncbi.nlm.nih.gov/pubmed/34196706
http://dx.doi.org/10.1093/jrr/rrab050

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