Normothermic ex vivo Heart Perfusion Combined With Melatonin Enhances Myocardial Protection in Rat Donation After Circulatory Death Hearts via Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis

OBJECTIVE: The adoption of hearts from donation after circulatory death (DCD) is a promising approach for the shortage of suitable organs in heart transplantation. However, DCD hearts suffer from serious ischemia/reperfusion injury (IRI). Recent studies demonstrate that nucleotide-binding oligomeriz...

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Detalles Bibliográficos
Autores principales: Lu, Jun, Xu, Liwei, Zeng, Zifeng, Xue, Chuqing, Li, Jiale, Chen, Xiong, Zhou, Pengyu, Lin, Shaoyan, Liao, Yuhui, Du, Xianjin, Yang, Ronghua, Zheng, Shaoyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438322/
https://www.ncbi.nlm.nih.gov/pubmed/34532321
http://dx.doi.org/10.3389/fcell.2021.733183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438322/
https://www.ncbi.nlm.nih.gov/pubmed/34532321
http://dx.doi.org/10.3389/fcell.2021.733183

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