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Carotenoid-Enriched Fractions From Spondias mombin Demonstrate HER2 ATP Kinase Domain Inhibition: Computational and In Vivo Animal Model of Breast Carcinoma Studies

Human epidermal growth factor 2 (HER2) is overexpressed in about 20% of breast cancer and is associated with a poor prognosis. We report in this study that carotenoid-enriched fractions from Spondias mombin demonstrate HER2 ATP kinase domain inhibition. HER2 breast carcinoma was modeled in female Wi...

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Detalles Bibliográficos
Autores principales:	Metibemu, Damilohun Samuel, Akinloye, Oluseyi Adeboye, Omotuyi, Idowu Olaposi, Okoye, Jude Ogechukwu, Popoola, Mustapha Ayodele, Akamo, Adio Jamiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438527/ https://www.ncbi.nlm.nih.gov/pubmed/34532287 http://dx.doi.org/10.3389/fonc.2021.687190

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