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Mycobacterium tuberculosis Rv0927c Inhibits NF-κB Pathway by Downregulating the Phosphorylation Level of IκBα and Enhances Mycobacterial Survival

Through long-term coevolution with its host, Mycobacterium tuberculosis (M. tuberculosis) uses multiple strategies to escape host defenses. The M. tuberculosis Rv0927c protein is predicted to be a short-chain dehydrogenase/reductase related to bacterial metabolism. However, the role of Rv0927c durin...

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Detalles Bibliográficos
Autores principales: Xia, Aihong, Li, Xin, Quan, Juanjuan, Chen, Xiang, Xu, Zhengzhong, Jiao, Xinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438533/
https://www.ncbi.nlm.nih.gov/pubmed/34531869
http://dx.doi.org/10.3389/fimmu.2021.721370