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Metformin attenuates angiotensin II-induced cardiomyocyte hypertrophy by upregulating the MuRF1 and MAFbx pathway

Pathological cardiac hypertrophy induced by aging and neurohumoral activation, such as angiotensin II (Ang II) activation, is an independent risk factor for heart failure. The muscle really interesting new gene-finger protein-1 (MuRF1) and muscle atrophy F-box (MAFbx) pathway has been previously rep...

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Detalles Bibliográficos
Autores principales:	Du, Fawang, Cao, Yalin, Ran, Yan, Wu, Qiang, Chen, Baolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438677/ https://www.ncbi.nlm.nih.gov/pubmed/34539827 http://dx.doi.org/10.3892/etm.2021.10665

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