Cargando…

Genetic variants associated with beta-cell function and insulin sensitivity potentially influence bile acid metabolites and gestational diabetes mellitus in a Chinese population

INTRODUCTION: To investigate associations between genetic variants related to beta-cell (BC) dysfunction or insulin resistance (IR) in type 2 diabetes (T2D) and bile acids (BAs), as well as the risk of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS: We organized a case-control stud...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Qiulun, Wang, Ying, Gu, Yuqin, Li, Jing, Wang, Hui, Leng, Junhong, Li, Weiqin, Yu, Zhijie, Hu, Gang, Ma, Ronald Ching Wan, Fang, Zhong-Ze, Yang, Xilin, Jiang, Guozhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438732/ https://www.ncbi.nlm.nih.gov/pubmed/34518156 http://dx.doi.org/10.1136/bmjdrc-2021-002287

Ejemplares similares

Zinc-Associated Variant in SLC30A8 Gene Interacts With Gestational Weight Gain on Postpartum Glycemic Changes: A Longitudinal Study in Women With Prior Gestational Diabetes Mellitus
por: Wang, Tiange, et al.
Publicado: (2016)

Sulfated Progesterone Metabolites That Enhance Insulin Secretion via TRPM3 Are Reduced in Serum From Women With Gestational Diabetes Mellitus
por: Fan, Hei Man, et al.
Publicado: (2022)

Urine Metabolite Profiles and Nutrient Intake Based on 4-Day Weighed Food Diary in Habitual Vegans, Vegetarians, and Omnivores
por: Lindqvist, Helen M, et al.
Publicado: (2020)

Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish
por: Axton, Elizabeth R, et al.
Publicado: (2019)

Association of the CDKAL1 gene polymorphism with gestational diabetes mellitus in Chinese women
por: Huang, Chengjing, et al.
Publicado: (2023)

Genetic Determinants of Glycemic Traits and the Risk of Gestational Diabetes Mellitus
por: Powe, Camille E., et al.
Publicado: (2018)

A Genome-Wide Association Study of Gestational Diabetes Mellitus in Korean Women
por: Kwak, Soo Heon, et al.
Publicado: (2012)

Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering
por: Powe, Camille E., et al.
Publicado: (2021)

Placental proteome abnormalities in women with gestational diabetes and large-for-gestational-age newborns
por: Assi, Emma, et al.
Publicado: (2020)

Epigenetic Regulation of Placenta-Specific 8 Contributes to Altered Function of Endothelial Colony-Forming Cells Exposed to Intrauterine Gestational Diabetes Mellitus
por: Blue, Emily K., et al.
Publicado: (2015)

Metabolomic Changes in Serum of Children with Different Clinical Diagnoses of Malnutrition(1)(2)(3)
por: Di Giovanni, Valeria, et al.
Publicado: (2016)

Metabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program
por: Walford, Geoffrey A., et al.
Publicado: (2016)

Metabolic Footprinting of Fermented Milk Consumption in Serum of Healthy Men
por: Pimentel, Grégory, et al.
Publicado: (2018)

The Plasma Proteome Is Associated with Anthropometric Status of Undernourished Nepalese School-Aged Children(1)(2)(3)
por: Lee, Sun Eun, et al.
Publicado: (2017)

Identification of Milk and Cheese Intake Biomarkers in Healthy Adults Reveals High Interindividual Variability of Lewis System–Related Oligosaccharides
por: Pimentel, Grégory, et al.
Publicado: (2020)

Personalized Profiling Reveals Donor- and Lactation-Specific Trends in the Human Milk Proteome and Peptidome
por: Zhu, Jing, et al.
Publicado: (2021)

DHA Supplementation Attenuates Inflammation-Associated Gene Expression in the Mammary Gland of Lactating Mothers Who Deliver Preterm
por: Adams, Joselyn M, et al.
Publicado: (2022)

Plasma MicroRNA Signature of Alcohol Consumption: The Rotterdam Study
por: Karabegović, Irma, et al.
Publicado: (2022)

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach
por: Floegel, Anna, et al.
Publicado: (2013)

Metabolites in the association between early-life famine exposure and type 2 diabetes in adulthood over a 5-year follow-up period
por: Wang, Yuying, et al.
Publicado: (2021)

Circulating Metabolites and Lipids Are Associated to Diabetic Retinopathy in Individuals With Type 1 Diabetes
por: Curovic, Viktor Rotbain, et al.
Publicado: (2020)

Circulating metabolites improve the prediction of renal impairment in patients with type 2 diabetes
por: Trischitta, Vincenzo, et al.
Publicado: (2023)

Associations of network-derived metabolite clusters with prevalent type 2 diabetes among adults of Puerto Rican descent
por: Haslam, Danielle E, et al.
Publicado: (2021)

Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations
por: Li, Mengying, et al.
Publicado: (2020)

Metabolite Profiling Reveals Normal Metabolic Control in Carriers of Mutations in the Glucokinase Gene (MODY2)
por: Spégel, Peter, et al.
Publicado: (2013)

Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans
por: Chen, Zsu-Zsu, et al.
Publicado: (2022)

Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth
por: Scholtens, Denise M., et al.
Publicado: (2016)

A Fecal Metabolite Signature of Impaired Fasting Glucose: Results From Two Independent Population-Based Cohorts
por: Nogal, Ana, et al.
Publicado: (2023)

A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans
por: Li, Huaixing, et al.
Publicado: (2013)

Differential DNA methylation profile in infants born small-for-gestational-age: association with markers of adiposity and insulin resistance from birth to age 24 months
por: Diaz, Marta, et al.
Publicado: (2020)

A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts
por: Tuomisto, Karolina, et al.
Publicado: (2022)

Human serum metabolomic analysis reveals progression for high blood pressure in type 2 diabetes mellitus
por: Zhang, Yin, et al.
Publicado: (2021)

Metabolomics-based multidimensional network biomarkers for diabetic retinopathy identification in patients with type 2 diabetes mellitus
por: Zuo, Jingjing, et al.
Publicado: (2021)

Molecular and clinical characteristics of monogenic diabetes mellitus in southern Chinese children with onset before 3 years of age
por: Lin, Yunting, et al.
Publicado: (2020)

Presence of PD-1 similarity genes in monocytes may promote the development of type 1 diabetes mellitus and poor prognosis of pancreatic cancer
por: Huang, Yuquan, et al.
Publicado: (2023)

Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study
por: Sobrin, Lucia, et al.
Publicado: (2017)

Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus
por: Alfaifi, Mohammed, et al.
Publicado: (2021)

Multiple HLA Epitopes Contribute to Type 1 Diabetes Susceptibility
por: Roark, Christina L., et al.
Publicado: (2014)

Association of G6PD variants with hemoglobin A1c and impact on diabetes diagnosis in East Asian individuals
por: Leong, Aaron, et al.
Publicado: (2020)

Methylation status of vault RNA 2-1 promoter is a predictor of glycemic response to glucagon-like peptide-1 analog therapy in type 2 diabetes mellitus
por: Lin, Chia-Hung, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s6nnh9cdoi76cjdk51ms6ljpui