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On timeline of enhancing testing-capacity of COVID-19: A case study via an optimal replacement model

Process of enhancing testing-capacity regarding COVID-19 is a topic of interest. This task of enhancing is constrained by socio-economic background of a country either in favorable or unfavorable ways. In this paper, we investigate timing of enhancing testing-capacity as an optimal problem, where th...

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Autores principales: Meththananda, R.G.U.I., Ganegoda, N.C., Perera, S.S.N., Erandi, K.K.W.H., Jayathunga, Y., Peiris, H.O.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438793/
https://www.ncbi.nlm.nih.gov/pubmed/34539099
http://dx.doi.org/10.1016/j.jprocont.2021.08.002
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author Meththananda, R.G.U.I.
Ganegoda, N.C.
Perera, S.S.N.
Erandi, K.K.W.H.
Jayathunga, Y.
Peiris, H.O.W.
author_facet Meththananda, R.G.U.I.
Ganegoda, N.C.
Perera, S.S.N.
Erandi, K.K.W.H.
Jayathunga, Y.
Peiris, H.O.W.
author_sort Meththananda, R.G.U.I.
collection PubMed
description Process of enhancing testing-capacity regarding COVID-19 is a topic of interest. This task of enhancing is constrained by socio-economic background of a country either in favorable or unfavorable ways. In this paper, we investigate timing of enhancing testing-capacity as an optimal problem, where the enhancement is quantified via number of tests as an instant measure and recovered portion as a long-term measure. The proposed work is structured analogous to an optimal machine replacement model based on a non-linear integral equation. Overall model is partially identifiable and compatible parameter estimations are carried out for a specific case study covering an early stage scenario. In addition, scenario development criteria on demand and effort for enhancing testing-capacity are introduced for predictions. In one numerical experiment, it is observed that frequency of enhancing testing-capacity starts decreasing after two increments indicating a favorable direction amidst effort constraints.
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spelling pubmed-84387932021-09-14 On timeline of enhancing testing-capacity of COVID-19: A case study via an optimal replacement model Meththananda, R.G.U.I. Ganegoda, N.C. Perera, S.S.N. Erandi, K.K.W.H. Jayathunga, Y. Peiris, H.O.W. J Process Control Article Process of enhancing testing-capacity regarding COVID-19 is a topic of interest. This task of enhancing is constrained by socio-economic background of a country either in favorable or unfavorable ways. In this paper, we investigate timing of enhancing testing-capacity as an optimal problem, where the enhancement is quantified via number of tests as an instant measure and recovered portion as a long-term measure. The proposed work is structured analogous to an optimal machine replacement model based on a non-linear integral equation. Overall model is partially identifiable and compatible parameter estimations are carried out for a specific case study covering an early stage scenario. In addition, scenario development criteria on demand and effort for enhancing testing-capacity are introduced for predictions. In one numerical experiment, it is observed that frequency of enhancing testing-capacity starts decreasing after two increments indicating a favorable direction amidst effort constraints. Elsevier Ltd. 2021-09 2021-08-12 /pmc/articles/PMC8438793/ /pubmed/34539099 http://dx.doi.org/10.1016/j.jprocont.2021.08.002 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Meththananda, R.G.U.I.
Ganegoda, N.C.
Perera, S.S.N.
Erandi, K.K.W.H.
Jayathunga, Y.
Peiris, H.O.W.
On timeline of enhancing testing-capacity of COVID-19: A case study via an optimal replacement model
title On timeline of enhancing testing-capacity of COVID-19: A case study via an optimal replacement model
title_full On timeline of enhancing testing-capacity of COVID-19: A case study via an optimal replacement model
title_fullStr On timeline of enhancing testing-capacity of COVID-19: A case study via an optimal replacement model
title_full_unstemmed On timeline of enhancing testing-capacity of COVID-19: A case study via an optimal replacement model
title_short On timeline of enhancing testing-capacity of COVID-19: A case study via an optimal replacement model
title_sort on timeline of enhancing testing-capacity of covid-19: a case study via an optimal replacement model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438793/
https://www.ncbi.nlm.nih.gov/pubmed/34539099
http://dx.doi.org/10.1016/j.jprocont.2021.08.002
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