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Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy

BACKGROUND: The prognosis for metastatic Ewing sarcoma family of tumors (EFT) is still poor despite high-dose chemotherapy and radiation treatment. Immunotherapies hold promise, but cancer antigen-targeting immunotherapies have largely failed to induce effective T cell receptor-mediated antitumor re...

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Detalles Bibliográficos
Autores principales:	Lin, Tsung-Yi, Park, Jeong A, Long, Alan, Guo, Hong-Fen, Cheung, Nai-Kong V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438958/ https://www.ncbi.nlm.nih.gov/pubmed/34497115 http://dx.doi.org/10.1136/jitc-2021-003114

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