Cargando…

The genomic profiling and MAMLD1 expression in human and canines with Cushing’s disease

BACKGROUND: Cushing’s disease (CD) is defined as hypercortisolemia caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (corticotroph PA) that afflicts humans and dogs. In order to map common aberrant genomic features of CD between humans and dogs, we performed genomic sequencin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Andrew, Neill, Stewart G., Newman, Scott, Tryfonidou, Marianna A., Ioachimescu, Adriana, Rossi, Michael R., Meij, Björn P., Oyesiku, Nelson M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438999/ https://www.ncbi.nlm.nih.gov/pubmed/34517852 http://dx.doi.org/10.1186/s12902-021-00845-z

Ejemplares similares

Racial Disparities in Acromegaly and Cushing’s Disease: A Referral Center Study in 241 Patients
por: Ioachimescu, Adriana G, et al.
Publicado: (2021)

SUN-LB074 Racial Distribution, Presentation and Outcome in Acromegaly and Cushing's Disease: A Tertiary Referral Center Study in 220 Patients
por: Goswami, Neevedita, et al.
Publicado: (2019)

Severe TSH Elevation and Pituitary Enlargement After Changing Thyroid Replacement to Compounded T4/T3 Therapy
por: Pappy, Adlai L., et al.
Publicado: (2016)

Parturition failure in mice lacking Mamld1
por: Miyado, Mami, et al.
Publicado: (2015)

Inflammatory profiles in canine intervertebral disc degeneration
por: Willems, Nicole, et al.
Publicado: (2016)

Notochordal-cell derived extracellular vesicles exert regenerative effects on canine and human nucleus pulposus cells
por: Bach, Frances, et al.
Publicado: (2017)

Canine Pituitary Organoids as 3D In Vitro Model for Cushing Disease
por: Sanders, Karin, et al.
Publicado: (2021)

MAMLD1 (CXorf6) is a New Gene for Hypospadias
por: Ogata, Tsutomu, et al.
Publicado: (2008)

Neuropsychological and Emotional Functioning in Patients with Cushing's Syndrome
por: Na, Sabrina, et al.
Publicado: (2020)

Circulating MicroRNAs as Non-invasive Biomarkers for Canine Cushing's Syndrome
por: Sanders, Karin, et al.
Publicado: (2021)

Effect of coculturing canine notochordal, nucleus pulposus and mesenchymal stromal cells for intervertebral disc regeneration
por: Arkesteijn, Irene TM, et al.
Publicado: (2015)

Biomechanical effects of a titanium intervertebral cage as a stand‐alone device, and in combination with locking plates in the canine caudal cervical spine
por: Beishuizen, Rick, et al.
Publicado: (2021)

Lack of Ubiquitin Specific Protease 8 (USP8) Mutations in Canine Corticotroph Pituitary Adenomas
por: Sbiera, Silviu, et al.
Publicado: (2016)

Enhanced Extracellular Matrix Breakdown Characterizes the Early Distraction Phase of Canine Knee Joint Distraction
por: Teunissen, Michelle, et al.
Publicado: (2021)

Transformation of a Silent Adrencorticotrophic Pituitary Tumor Into Central Nervous System Melanoma
por: Miller, Brandon A., et al.
Publicado: (2013)

Broad Phenotypes of Disorders/Differences of Sex Development in MAMLD1 Patients Through Oligogenic Disease
por: Flück, Christa E., et al.
Publicado: (2019)

Pedicle screw-rod fixation: a feasible treatment for dogs with severe degenerative lumbosacral stenosis
por: Tellegen, Anna R., et al.
Publicado: (2015)

Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model
por: Willemsen, Koen, et al.
Publicado: (2021)

Human MAMLD1 Gene Variations Seem Not Sufficient to Explain a 46,XY DSD Phenotype
por: Camats, Núria, et al.
Publicado: (2015)

Disorders of Sex Development in Individuals Harbouring MAMLD1 Variants: WES and Interactome Evidence of Oligogenic Inheritance
por: Li, Lele, et al.
Publicado: (2020)

Mamld1 Knockdown Reduces Testosterone Production and Cyp17a1 Expression in Mouse Leydig Tumor Cells
por: Nakamura, Michiko, et al.
Publicado: (2011)

Biomechanical evaluation of a novel biomimetic artificial intervertebral disc in canine cervical cadaveric spines
por: Jacobs, Celien A. M., et al.
Publicado: (2023)

Patient-specific 3D-printed shelf implant for the treatment of hip dysplasia tested in an experimental animal pilot in canines
por: Willemsen, Koen, et al.
Publicado: (2022)

Canine Degenerative Lumbosacral Stenosis: Prevalence, Impact And Management Strategies
por: Worth, Andrew, et al.
Publicado: (2019)

Consecutive resections of double pituitary adenoma for resolution of Cushing disease: illustrative case
por: Armstrong, Stephanie A, et al.
Publicado: (2023)

Safety of intradiscal injection and biocompatibility of polyester amide microspheres in a canine model predisposed to intervertebral disc degeneration
por: Willems, Nicole, et al.
Publicado: (2015)

Screening of MAMLD1 Mutations in 70 Children with 46,XY DSD: Identification and Functional Analysis of Two New Mutations
por: Kalfa, Nicolas, et al.
Publicado: (2012)

Childhood supratentorial ependymomas with YAP1‐MAMLD1 fusion: an entity with characteristic clinical, radiological, cytogenetic and histopathological features
por: Andreiuolo, Felipe, et al.
Publicado: (2018)

Knockout of Murine Mamld1 Impairs Testicular Growth and Daily Sperm Production but Permits Normal Postnatal Androgen Production and Fertility
por: Miyado, Mami, et al.
Publicado: (2017)

Clinical and molecular spectrum of 46,XY disorders of sex development that harbour MAMLD1 variations: case series and review of literature
por: Li, Lele, et al.
Publicado: (2020)

A New MAMLD1 Variant in an Infant With Microphallus and Hypospadias With Hormonal Pattern Suggesting Partial Hypogonadotropic Hypogonadism—Case Report
por: Yeste, Diego, et al.
Publicado: (2022)

Growth plate expression profiling: Large and small breed dogs provide new insights in endochondral bone formation
por: Teunissen, Michelle, et al.
Publicado: (2017)

Potential regenerative treatment strategies for intervertebral disc degeneration in dogs
por: Bach, Frances C, et al.
Publicado: (2014)

Notochordal cell matrix: An inhibitor of neurite and blood vessel growth?
por: de Vries, Stefan A.H., et al.
Publicado: (2018)

Intradiscal application of rhBMP-7 does not induce regeneration in a canine model of spontaneous intervertebral disc degeneration
por: Willems, Nicole, et al.
Publicado: (2015)

Biologic canine and human intervertebral disc repair by notochordal cell-derived matrix: from bench towards bedside
por: Bach, Frances C., et al.
Publicado: (2018)

Melanocortin 2 Receptor Antagonists in Canine Cushing’s Disease: In Vitro Studies
por: Sanders, Karin, et al.
Publicado: (2021)

Aquaporin expression in the human and canine intervertebral disc during maturation and degeneration
por: Snuggs, Joseph W., et al.
Publicado: (2019)

Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics
por: Franceschini, Natasja, et al.
Publicado: (2021)

Distinct serum steroid profiles between adrenal Cushing syndrome and Cushing disease
por: Gao, Chang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_o2nihetqf23ftlgh6hvbrbd20g