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High-yield synthesis and purification of recombinant human GABA transaminase for high-throughput screening assays

Many studies have focussed on modulating the activity of γ-aminobutyric acid transaminase (GABA-T), a GABA-catabolizing enzyme, for treating neurological diseases, such as epilepsy and drug addiction. Nevertheless, human GABA-T synthesis and purification have not been established. Thus, biochemical...

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Detalles Bibliográficos
Autores principales:	Park, Mingu Gordon, Han, Ah-reum, Kim, Su Yeon, Kim, Tai Young, Kim, Ho Min, Lee, C. Justin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439235/ https://www.ncbi.nlm.nih.gov/pubmed/34514924 http://dx.doi.org/10.1080/14756366.2021.1975697

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