Cargando…

Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass

Calf circumference (CC) has been established as a marker of muscle mass (MM) with good performance for predicting survival in individuals with cancer. The study aims to determine the prevalence of sarcopenia according to the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria a...

Descripción completa

Detalles Bibliográficos
Autores principales: Trussardi Fayh, Ana Paula, de Sousa, Iasmin Matias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439478/
https://www.ncbi.nlm.nih.gov/pubmed/34520502
http://dx.doi.org/10.1371/journal.pone.0257446
_version_ 1783752533599059968
author Trussardi Fayh, Ana Paula
de Sousa, Iasmin Matias
author_facet Trussardi Fayh, Ana Paula
de Sousa, Iasmin Matias
author_sort Trussardi Fayh, Ana Paula
collection PubMed
description Calf circumference (CC) has been established as a marker of muscle mass (MM) with good performance for predicting survival in individuals with cancer. The study aims to determine the prevalence of sarcopenia according to the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria and to evaluate the accuracy of sarcopenia using low CC relative to MM assessment by computed tomography (CT) at third lumbar vertebra level (L3) as a reference. Cross-sectional study with cancer patients aged ≥ 60 years. Data included socio-demographic, clinical and anthropometric variables. MM was assessed by CC and by CT images at the L3. Sarcopenia was diagnosed according to the EWGSOP2 criteria: a) low handgrip strength (HGS) + reduced MM evaluated by CT; and b) low HGS + low CC. Pearson’s correlation, accuracy, sensitivity, specificity, positive predictive and negative predictive value were analyzed. A total of 108 patients were evaluated, age of 70.6 ± 7.4 years (mean ± standard deviation). The prevalence of sarcopenia was of 24.1% (low MM) and 25.9% (low CC). The Kappa test showed a substantial agreement (K = 0.704), 81% sensitivity, and 92% specificity. Although the EWGSOP2 advises that we should use CC measures in the algorithm for sarcopenia when no other MM diagnostic methods are available, the findings allow the use of CC instead of MM by CT in cancer patients.
format Online
Article
Text
id pubmed-8439478
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-84394782021-09-15 Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass Trussardi Fayh, Ana Paula de Sousa, Iasmin Matias PLoS One Research Article Calf circumference (CC) has been established as a marker of muscle mass (MM) with good performance for predicting survival in individuals with cancer. The study aims to determine the prevalence of sarcopenia according to the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria and to evaluate the accuracy of sarcopenia using low CC relative to MM assessment by computed tomography (CT) at third lumbar vertebra level (L3) as a reference. Cross-sectional study with cancer patients aged ≥ 60 years. Data included socio-demographic, clinical and anthropometric variables. MM was assessed by CC and by CT images at the L3. Sarcopenia was diagnosed according to the EWGSOP2 criteria: a) low handgrip strength (HGS) + reduced MM evaluated by CT; and b) low HGS + low CC. Pearson’s correlation, accuracy, sensitivity, specificity, positive predictive and negative predictive value were analyzed. A total of 108 patients were evaluated, age of 70.6 ± 7.4 years (mean ± standard deviation). The prevalence of sarcopenia was of 24.1% (low MM) and 25.9% (low CC). The Kappa test showed a substantial agreement (K = 0.704), 81% sensitivity, and 92% specificity. Although the EWGSOP2 advises that we should use CC measures in the algorithm for sarcopenia when no other MM diagnostic methods are available, the findings allow the use of CC instead of MM by CT in cancer patients. Public Library of Science 2021-09-14 /pmc/articles/PMC8439478/ /pubmed/34520502 http://dx.doi.org/10.1371/journal.pone.0257446 Text en © 2021 Trussardi Fayh, de Sousa https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Trussardi Fayh, Ana Paula
de Sousa, Iasmin Matias
Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass
title Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass
title_full Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass
title_fullStr Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass
title_full_unstemmed Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass
title_short Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass
title_sort comparison of revised ewgsop2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439478/
https://www.ncbi.nlm.nih.gov/pubmed/34520502
http://dx.doi.org/10.1371/journal.pone.0257446
work_keys_str_mv AT trussardifayhanapaula comparisonofrevisedewgsop2criteriaofsarcopeniainpatientswithcancerusingdifferentparametersofmusclemass
AT desousaiasminmatias comparisonofrevisedewgsop2criteriaofsarcopeniainpatientswithcancerusingdifferentparametersofmusclemass