Short- and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis

Development of cervical cancer is directly associated with integration of human papillomavirus (HPV) genomes into host chromosomes and subsequent modulation of HPV oncogene expression, which correlates with multi-layered epigenetic changes at the integrated HPV genomes. However, the process of integ...

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Detalles Bibliográficos
Autores principales: Groves, Ian J., Drane, Emma L. A., Michalski, Marco, Monahan, Jack M., Scarpini, Cinzia G., Smith, Stephen P., Bussotti, Giovanni, Várnai, Csilla, Schoenfelder, Stefan, Fraser, Peter, Enright, Anton J., Coleman, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439666/
https://www.ncbi.nlm.nih.gov/pubmed/34432858
http://dx.doi.org/10.1371/journal.ppat.1009875

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