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A pH-engineering regenerative DNA tetrahedron ECL biosensor for the assay of SARS-CoV-2 RdRp gene based on CRISPR/Cas12a trans-activity

In this work, we constructed an exonuclease III cleavage reaction-based isothermal amplification of nucleic acids with CRISPR/Cas12a-mediated pH-induced regenerative Electrochemiluminescence (ECL) biosensor for ultrasensitive and specific detection of SARS-CoV-2 nucleic acids for SARS-CoV-2 diagnosi...

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Detalles Bibliográficos
Autores principales:	Zhang, Kai, Fan, Zhenqiang, Ding, Yuedi, Xie, Minhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440004/ https://www.ncbi.nlm.nih.gov/pubmed/34539224 http://dx.doi.org/10.1016/j.cej.2021.132472

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