Cargando…

Comparison of Efficacy and Safety of Recombinant Human Prourokinase and Alteplase in the Treatment of STEMI and Analysis of Influencing Factors of Efficacy

OBJECTIVE: To compare the efficacy and safety of recombinant human prourokinase (rhPro-UK) and alteplase for thrombolytic therapy in acute ST-segment elevation myocardial infarction (STEMI) and to analyze the related factors affecting efficacy. METHODS: From January 2017 to December 2019, 100 patien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yizhou, Yang, Yulin, Li, Ying, Peng, Xiaoqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440075/ https://www.ncbi.nlm.nih.gov/pubmed/34531919 http://dx.doi.org/10.1155/2021/6702965

Ejemplares similares

Safety and efficacy of intracoronary recombinant human prourokinase administration in patients with acute myocardial infarction and ST‑segment elevation: A meta‑analysis of randomized controlled trials
por: Fan, Gang, et al.
Publicado: (2022)

Cardiotonic Pills Plus Recombinant Human Prourokinase Ameliorates Atherosclerotic Lesions in LDLR(–/–) Mice
por: Deng, Jing-Na, et al.
Publicado: (2019)

Efficacy and Safety of Recombinant Human Prourokinase in the Treatment of Acute Ischemic Stroke Within 4.5 Hours of Stroke Onset: A Phase 3 Randomized Clinical Trial
por: Song, Haiqing, et al.
Publicado: (2023)

Safety and efficacy of alteplase in the treatment of acute ischemic stroke
por: Micieli, Giuseppe, et al.
Publicado: (2009)

Safety and efficacy study of prourokinase injection during primary percutaneous coronary intervention in acute ST-segment elevation myocardial infarction
por: Jiang, Wenlong, et al.
Publicado: (2020)

USE OF INTRACORONARY ALTEPLASE IN A COVID STEMI PATIENT WITH LIMITED DISTAL FLOW
por: Jolly, George, et al.
Publicado: (2021)

Alteplase/epoprostenol: Lack of efficacy: case report
Publicado: (2022)

Efficacy and safety of intracoronary prourokinase during percutaneous coronary intervention in treating ST-segment elevation myocardial infarction patients: a randomized, controlled study
por: Wu, Yanqiang, et al.
Publicado: (2020)

Evaluation of efficacy and safety of Reteplase and Alteplase in the treatment of hyper-acute cerebral infarction
por: Lin, Zhi-Jian, et al.
Publicado: (2018)

No sex difference was found in the safety and efficacy of intravenous alteplase before endovascular therapy
por: Fang, Min, et al.
Publicado: (2022)

Safety and Efficacy of Thrombolytic Therapy Using rt-PA (Alteplase) in Acute Ischemic Stroke
por: Sivanandy, Palanisamy, et al.
Publicado: (2011)

Alteplase/enoxaparin-sodium: Lack of efficacy: case report
Publicado: (2021)

Concomitant secretion of prourokinase and of a plasminogen activator- specific inhibitor by cultured human monocytes-macrophages
Publicado: (1984)

Safety and Efficacy of Intravenous Alteplase before Endovascular Thrombectomy: A Pooled Analysis with Focus on the Elderly
por: Honig, Asaf, et al.
Publicado: (2022)

Efficacy and safety of low dose alteplase for intravenous thrombolysis in Asian stroke patients: a meta-analysis
por: Tan, Ge, et al.
Publicado: (2017)

Tenecteplase and Alteplase for Thrombolysis of Acute Ischemic Stroke within 4.5 Hours: An Efficacy and Safety Study
por: Dhar, Nikita, et al.
Publicado: (2022)

Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion
Publicado: (1989)

Safety and efficacy of tenecteplase versus alteplase in acute coronary syndrome: a systematic review and meta-analysis of randomized trials
por: Guillermin, Alexandre, et al.
Publicado: (2016)

Tenecteplase versus Alteplase for the Management of Acute Ischemic Stroke in a Low-income Country–Nepal: Cost, Efficacy, and Safety
por: Nepal, Gaurav, et al.
Publicado: (2018)

Real-world comparative safety and efficacy of tenecteplase versus alteplase in acute ischemic stroke patients with large vessel occlusion
por: Psychogios, Klearchos, et al.
Publicado: (2021)

Mutant Prourokinase with Adjunctive C1-Inhibitor Is an Effective and Safer Alternative to tPA in Rat Stroke
por: Tomasi, Simone, et al.
Publicado: (2011)

Early changes in fibrinogen after administration of alteplase are associated with the short-term efficacy of thrombolysis
por: Lu, Tao, et al.
Publicado: (2018)

Effect of intravenous thrombolysis with alteplase on clinical efficacy, inflammatory factors, and neurological function in patients with acute cerebral infarction
por: Wang, Jinhua, et al.
Publicado: (2021)

Polylactide-Based Stent Coatings: Biodegradable Polymeric Coatings Capable of Maintaining Sustained Release of the Thrombolytic Enzyme Prourokinase
por: Baikin, Alexander S., et al.
Publicado: (2019)

Catheter-Directed Thrombolysis With a Continuous Infusion of Low-Dose Alteplase for Subacute Proximal Venous Thrombosis: Efficacy and Safety Compared to Urokinase
por: Gong, Maofeng, et al.
Publicado: (2018)

Efficacy and Safety of Thrombectomy Combined with Intracoronary Administration of Tirofiban in ST-segment Elevation Myocardial Infarction (STEMI)
por: Gao, Lu, et al.
Publicado: (2016)

Recombinant Human Insulins – Clinical Efficacy and Safety in Diabetes Therapy
por: Landgraf, Wolfgang, et al.
Publicado: (2016)

The effects of prehospital system delays on the treatment efficacy of STEMI patients
por: Żurowska-Wolak, Magdalena, et al.
Publicado: (2019)

Efficacy and safety of intravenous thrombolysis with alteplase for treating acute ischemic stroke at different time windows: A protocol for systematic review and meta-analysis
por: Huang, Baogang, et al.
Publicado: (2020)

The efficacy and safety of tenecteplase versus alteplase for acute ischemic stroke: an updated systematic review, pairwise, and network meta-analysis of randomized controlled trials
por: Abuelazm, Mohamed, et al.
Publicado: (2022)

Effectiveness and Safety of Tecneplase vs. Alteplase in the Acute Treatment of Ischemic Stroke
por: Estella, Ángel, et al.
Publicado: (2022)

Fingolimod enhances the efficacy of delayed alteplase administration in acute ischemic stroke by promoting anterograde reperfusion and retrograde collateral flow
por: Tian, De‐Cai, et al.
Publicado: (2018)

Clinical efficacy and safety of hypernormal shortened door to needle time (DNT) plus individualized low-dose alteplase therapy in treating acute ischemic stroke
por: Zheng, Mei, et al.
Publicado: (2016)

Effect of alteplase on platelet function and receptor expression
por: Lu, Jun, et al.
Publicado: (2019)

Replacing Alteplase with Tenecteplase: Is the Time Ripe?
por: Singh, Nishita, et al.
Publicado: (2023)

STEMI or non-STEMI: that is the question
por: Camaro, Cyril, et al.
Publicado: (2015)

The efficacy and safety of the short‐term combination therapy with ticagrelor and PPIs or H2RA in patients with acute STEMI who underwent emergency PCI
por: Wei, Peng, et al.
Publicado: (2021)

Alteplase/heparin/low-molecular-weight-heparins: Lack of efficacy, femoral haemorrhage and jugular haemorrhage: 5 case reports
Publicado: (2020)

Targeting the PAI-1 Mechanism with a Small Peptide Increases the Efficacy of Alteplase in a Rabbit Model of Chronic Empyema
por: Florova, Galina, et al.
Publicado: (2023)

Recombinant human TNK tissue-type plasminogen activator (rhTNK-tPA) versus alteplase (rt-PA) as fibrinolytic therapy for acute ST-segment elevation myocardial infarction (China TNK STEMI): protocol for a randomised, controlled, non-inferiority trial
por: Wang, Hai-bo, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_boelngbvc5jgj0a0q2pg69h0e7