Integrating PCR-free amplification and synergistic sensing for ultrasensitive and rapid CRISPR/Cas12a-based SARS-CoV-2 antigen detection

Antigen detection provides particularly valuable information for medical diagnoses; however, the current detection methods are less sensitive and accurate than nucleic acid analysis. The combination of CRISPR/Cas12a and aptamers provides a new detection paradigm, but sensitive sensing and stable amp...

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Detalles Bibliográficos
Autores principales: Zhao, Xiangxiang, Wang, Zhengduo, Yang, Bowen, Li, Zilong, Tong, Yaojun, Bi, Yuhai, Li, Zhenghong, Xia, Xuekui, Chen, Xiangyin, Zhang, Lixin, Wang, Weishan, Tan, Gao-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440162/
https://www.ncbi.nlm.nih.gov/pubmed/34541346
http://dx.doi.org/10.1016/j.synbio.2021.09.007

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