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Role of FMRP in rapid antidepressant effects and synapse regulation

Rapid antidepressants are novel treatments for major depressive disorder (MDD) and work by blocking N-methyl-D-aspartate receptors (NMDARs), which, in turn, activate the protein synthesis pathway regulated by mechanistic/mammalian target of rapamycin complex 1 (mTORC1). Our recent work demonstrates...

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Detalles Bibliográficos
Autores principales:	Heaney, Chelcie F., Namjoshi, Sanjeev V., Uneri, Ayse, Bach, Eva C., Weiner, Jeffrey L., Raab-Graham, Kimberly F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440195/ https://www.ncbi.nlm.nih.gov/pubmed/33432187 http://dx.doi.org/10.1038/s41380-020-00977-z

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