In vivo generation of collagen specific Tregs with AAV8 suppresses autoimmune responses and arthritis in DBA1 mice through IL10 production

Available therapeutics for autoimmune disorders focused on mitigating symptoms, rather than treating the cause of the disorder. A novel approach using adeno-associated virus (AAV) could restore tolerance to the autoimmune targets and provide a permanent treatment for autoimmune diseases. Here, we ev...

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Detalles Bibliográficos
Autores principales: Wade, Matthew, Fausther-Bovendo, Hugues, De La Vega, Marc-Antoine, Kobinger, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440515/
https://www.ncbi.nlm.nih.gov/pubmed/34521922
http://dx.doi.org/10.1038/s41598-021-97739-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440515/
https://www.ncbi.nlm.nih.gov/pubmed/34521922
http://dx.doi.org/10.1038/s41598-021-97739-w

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