HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants

G protein-coupled receptors (GPCRs) are notoriously difficult to detect in native tissues. In an effort to resolve this problem, we have developed a novel mouse model by fusing the hemagglutinin (HA)-epitope tag sequence to the amino-terminus of the µ-opioid receptor (MOP). Although HA-MOP knock-in...

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Detalles Bibliográficos
Autores principales: Fritzwanker, Sebastian, Moulédous, Lionel, Mollereau, Catherine, Froment, Carine, Burlet-Schiltz, Odile, Effah, Felix, Bailey, Alexis, Spetea, Mariana, Reinscheid, Rainer K., Schulz, Stefan, Kliewer, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440528/
https://www.ncbi.nlm.nih.gov/pubmed/34522000
http://dx.doi.org/10.1038/s42003-021-02580-6

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