Multi-region exome sequencing reveals the intratumoral heterogeneity of surgically resected small cell lung cancer

Small cell lung cancer (SCLC) is a highly malignant tumor which is eventually refractory to any treatment. Intratumoral heterogeneity (ITH) may contribute to treatment failure. However, the extent of ITH in SCLC is still largely unknown. Here, we subject 120 tumor samples from 40 stage I-III SCLC pa...

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Detalles Bibliográficos
Autores principales: Zhou, Huaqiang, Hu, Yi, Luo, Rongzhen, Zhao, Yuanyuan, Pan, Hui, Ji, Liyan, Zhou, Ting, Zhang, Lanjun, Long, Hao, Fu, Jianhua, Wen, Zhesheng, Wang, Siyu, Wang, Xin, Lin, Peng, Yang, Haoxian, Wang, Junye, Song, Mengmeng, Yi, Xin, Yang, Ling, Xia, Xuefang, Guan, Yanfang, Fang, Wenfeng, Yang, Yunpeng, Hong, Shaodong, Huang, Yan, Li, Pansong, Zhang, Yaxiong, Zhou, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440529/
https://www.ncbi.nlm.nih.gov/pubmed/34521849
http://dx.doi.org/10.1038/s41467-021-25787-x

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