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Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients

To test diagnostic accuracy of changes in thickness (TH) and cross-sectional area (CSA) of muscle ultrasound for diagnosis of intensive care unit acquired weakness (ICU-AW). Fully conscious patients were subjected to muscle ultrasonography including measuring the changes in TH and CSA of biceps brac...

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Autores principales: Zhang, Weiqing, Wu, Jun, Gu, Qiuying, Gu, Yanting, Zhao, Yujin, Ge, Xiaoying, Sun, Xiaojing, Lian, Jun, Zeng, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440559/
https://www.ncbi.nlm.nih.gov/pubmed/34521934
http://dx.doi.org/10.1038/s41598-021-97680-y
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author Zhang, Weiqing
Wu, Jun
Gu, Qiuying
Gu, Yanting
Zhao, Yujin
Ge, Xiaoying
Sun, Xiaojing
Lian, Jun
Zeng, Qian
author_facet Zhang, Weiqing
Wu, Jun
Gu, Qiuying
Gu, Yanting
Zhao, Yujin
Ge, Xiaoying
Sun, Xiaojing
Lian, Jun
Zeng, Qian
author_sort Zhang, Weiqing
collection PubMed
description To test diagnostic accuracy of changes in thickness (TH) and cross-sectional area (CSA) of muscle ultrasound for diagnosis of intensive care unit acquired weakness (ICU-AW). Fully conscious patients were subjected to muscle ultrasonography including measuring the changes in TH and CSA of biceps brachii (BB) muscle, vastus intermedius (VI) muscle, and rectus femoris (RF) muscles over time. 37 patients underwent muscle ultrasonography on admission day, day 4, day 7, and day 10 after ICU admission, Among them, 24 were found to have ICW-AW. Changes in muscle TH and CSA of RF muscle on the right side showed remarkably higher ROC-AUC and the range was from 0.734 to 0.888. Changes in the TH of VI muscle had fair ROC-AUC values which were 0.785 on the left side and 0.779 on the right side on the 10th day after ICU admission. Additionally, Sequential Organ Failure Assessment (SOFA), Acute Physiology, and Chronic Health Evaluation II (APACHE II) scores also showed good discriminative power on the day of admission (ROC-AUC 0.886 and 0.767, respectively). Ultrasonography of changes in muscles, especially in the TH of VI muscle on both sides and CSA of RF muscle on the right side, presented good diagnostic accuracy. However, SOFA and APACHE II scores are better options for early ICU-AW prediction due to their simplicity and time efficiency.
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spelling pubmed-84405592021-09-15 Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients Zhang, Weiqing Wu, Jun Gu, Qiuying Gu, Yanting Zhao, Yujin Ge, Xiaoying Sun, Xiaojing Lian, Jun Zeng, Qian Sci Rep Article To test diagnostic accuracy of changes in thickness (TH) and cross-sectional area (CSA) of muscle ultrasound for diagnosis of intensive care unit acquired weakness (ICU-AW). Fully conscious patients were subjected to muscle ultrasonography including measuring the changes in TH and CSA of biceps brachii (BB) muscle, vastus intermedius (VI) muscle, and rectus femoris (RF) muscles over time. 37 patients underwent muscle ultrasonography on admission day, day 4, day 7, and day 10 after ICU admission, Among them, 24 were found to have ICW-AW. Changes in muscle TH and CSA of RF muscle on the right side showed remarkably higher ROC-AUC and the range was from 0.734 to 0.888. Changes in the TH of VI muscle had fair ROC-AUC values which were 0.785 on the left side and 0.779 on the right side on the 10th day after ICU admission. Additionally, Sequential Organ Failure Assessment (SOFA), Acute Physiology, and Chronic Health Evaluation II (APACHE II) scores also showed good discriminative power on the day of admission (ROC-AUC 0.886 and 0.767, respectively). Ultrasonography of changes in muscles, especially in the TH of VI muscle on both sides and CSA of RF muscle on the right side, presented good diagnostic accuracy. However, SOFA and APACHE II scores are better options for early ICU-AW prediction due to their simplicity and time efficiency. Nature Publishing Group UK 2021-09-14 /pmc/articles/PMC8440559/ /pubmed/34521934 http://dx.doi.org/10.1038/s41598-021-97680-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhang, Weiqing
Wu, Jun
Gu, Qiuying
Gu, Yanting
Zhao, Yujin
Ge, Xiaoying
Sun, Xiaojing
Lian, Jun
Zeng, Qian
Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients
title Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients
title_full Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients
title_fullStr Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients
title_full_unstemmed Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients
title_short Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients
title_sort changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440559/
https://www.ncbi.nlm.nih.gov/pubmed/34521934
http://dx.doi.org/10.1038/s41598-021-97680-y
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