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Laser isotope separation of (176)Lu through off-the-shelf lasers
We propose a novel and simple method for the laser isotope separation of (176)Lu a precursor for the production of (177)Lu medical isotope. The physics of the laser-atom interaction has been studied through the dynamics of the atomic level populations using the density matrix formalism. It has been...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440568/ https://www.ncbi.nlm.nih.gov/pubmed/34521914 http://dx.doi.org/10.1038/s41598-021-97773-8 |
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author | Suryanarayana, M. V. Sankari, M. |
author_facet | Suryanarayana, M. V. Sankari, M. |
author_sort | Suryanarayana, M. V. |
collection | PubMed |
description | We propose a novel and simple method for the laser isotope separation of (176)Lu a precursor for the production of (177)Lu medical isotope. The physics of the laser-atom interaction has been studied through the dynamics of the atomic level populations using the density matrix formalism. It has been shown that a combination of cw excitation lasers and pulsed ionization laser can be used for the laser isotope separation of (176)Lu. The optimum conditions for the efficient and selective separation of (176)Lu have been derived by studying the time evolution of level population under laser excitation. It has also been shown that, it might be possible to produce ~ 100% enriched (176)Lu isotope at a rate of 5 mg/h, which is higher than all previously reported methods so far. The isotope separation process proposed can be easily adopted using off-the-shelf lasers, for similar atomic systems. |
format | Online Article Text |
id | pubmed-8440568 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84405682021-09-15 Laser isotope separation of (176)Lu through off-the-shelf lasers Suryanarayana, M. V. Sankari, M. Sci Rep Article We propose a novel and simple method for the laser isotope separation of (176)Lu a precursor for the production of (177)Lu medical isotope. The physics of the laser-atom interaction has been studied through the dynamics of the atomic level populations using the density matrix formalism. It has been shown that a combination of cw excitation lasers and pulsed ionization laser can be used for the laser isotope separation of (176)Lu. The optimum conditions for the efficient and selective separation of (176)Lu have been derived by studying the time evolution of level population under laser excitation. It has also been shown that, it might be possible to produce ~ 100% enriched (176)Lu isotope at a rate of 5 mg/h, which is higher than all previously reported methods so far. The isotope separation process proposed can be easily adopted using off-the-shelf lasers, for similar atomic systems. Nature Publishing Group UK 2021-09-14 /pmc/articles/PMC8440568/ /pubmed/34521914 http://dx.doi.org/10.1038/s41598-021-97773-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Suryanarayana, M. V. Sankari, M. Laser isotope separation of (176)Lu through off-the-shelf lasers |
title | Laser isotope separation of (176)Lu through off-the-shelf lasers |
title_full | Laser isotope separation of (176)Lu through off-the-shelf lasers |
title_fullStr | Laser isotope separation of (176)Lu through off-the-shelf lasers |
title_full_unstemmed | Laser isotope separation of (176)Lu through off-the-shelf lasers |
title_short | Laser isotope separation of (176)Lu through off-the-shelf lasers |
title_sort | laser isotope separation of (176)lu through off-the-shelf lasers |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440568/ https://www.ncbi.nlm.nih.gov/pubmed/34521914 http://dx.doi.org/10.1038/s41598-021-97773-8 |
work_keys_str_mv | AT suryanarayanamv laserisotopeseparationof176luthroughofftheshelflasers AT sankarim laserisotopeseparationof176luthroughofftheshelflasers |