Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions

The Aldehyde dehydrogenase (ALDH) superfamily comprises a group of enzymes involved in the scavenging of toxic aldehyde molecules by converting them into their corresponding non-toxic carboxylic acids. A genome-wide study in potato identified a total of 22 ALDH genes grouped into ten families that a...

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Autores principales: Islam, Md. Sifatul, Hasan, Md. Soyib, Hasan, Md. Nazmul, Prodhan, Shamsul H., Islam, Tahmina, Ghosh, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440639/
https://www.ncbi.nlm.nih.gov/pubmed/34521910
http://dx.doi.org/10.1038/s41598-021-97691-9
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author Islam, Md. Sifatul
Hasan, Md. Soyib
Hasan, Md. Nazmul
Prodhan, Shamsul H.
Islam, Tahmina
Ghosh, Ajit
author_facet Islam, Md. Sifatul
Hasan, Md. Soyib
Hasan, Md. Nazmul
Prodhan, Shamsul H.
Islam, Tahmina
Ghosh, Ajit
author_sort Islam, Md. Sifatul
collection PubMed
description The Aldehyde dehydrogenase (ALDH) superfamily comprises a group of enzymes involved in the scavenging of toxic aldehyde molecules by converting them into their corresponding non-toxic carboxylic acids. A genome-wide study in potato identified a total of 22 ALDH genes grouped into ten families that are presented unevenly throughout all the 12 chromosomes. Based on the evolutionary analysis of ALDH proteins from different plant species, ALDH2 and ALDH3 were found to be the most abundant families in the plant, while ALDH18 was found to be the most distantly related one. Gene expression analysis revealed that the expression of StALDH genes is highly tissue-specific and divergent in various abiotic, biotic, and hormonal treatments. Structural modelling and functional analysis of selected StALDH members revealed conservancy in their secondary structures and cofactor binding sites. Taken together, our findings provide comprehensive information on the ALDH gene family in potato that will help in developing a framework for further functional studies.
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spelling pubmed-84406392021-09-20 Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions Islam, Md. Sifatul Hasan, Md. Soyib Hasan, Md. Nazmul Prodhan, Shamsul H. Islam, Tahmina Ghosh, Ajit Sci Rep Article The Aldehyde dehydrogenase (ALDH) superfamily comprises a group of enzymes involved in the scavenging of toxic aldehyde molecules by converting them into their corresponding non-toxic carboxylic acids. A genome-wide study in potato identified a total of 22 ALDH genes grouped into ten families that are presented unevenly throughout all the 12 chromosomes. Based on the evolutionary analysis of ALDH proteins from different plant species, ALDH2 and ALDH3 were found to be the most abundant families in the plant, while ALDH18 was found to be the most distantly related one. Gene expression analysis revealed that the expression of StALDH genes is highly tissue-specific and divergent in various abiotic, biotic, and hormonal treatments. Structural modelling and functional analysis of selected StALDH members revealed conservancy in their secondary structures and cofactor binding sites. Taken together, our findings provide comprehensive information on the ALDH gene family in potato that will help in developing a framework for further functional studies. Nature Publishing Group UK 2021-09-14 /pmc/articles/PMC8440639/ /pubmed/34521910 http://dx.doi.org/10.1038/s41598-021-97691-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Islam, Md. Sifatul
Hasan, Md. Soyib
Hasan, Md. Nazmul
Prodhan, Shamsul H.
Islam, Tahmina
Ghosh, Ajit
Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions
title Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions
title_full Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions
title_fullStr Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions
title_full_unstemmed Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions
title_short Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions
title_sort genome-wide identification, evolution, and transcript profiling of aldehyde dehydrogenase superfamily in potato during development stages and stress conditions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440639/
https://www.ncbi.nlm.nih.gov/pubmed/34521910
http://dx.doi.org/10.1038/s41598-021-97691-9
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