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The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites

Cruzipains are the main papain-like cysteine proteases of Trypanosoma cruzi, the protozoan parasite that causes Chagas disease. Encoded by a multigenic family, previous studies have estimated the presence of dozens of copies spread over multiple chromosomes in different parasite strains. Here, we de...

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Detalles Bibliográficos
Autores principales: Santos, Viviane Corrêa, Oliveira, Antonio Edson Rocha, Campos, Augusto César Broilo, Reis-Cunha, João Luís, Bartholomeu, Daniella Castanheira, Teixeira, Santuza Maria Ribeiro, Lima, Ana Paula C. A., Ferreira, Rafaela Salgado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440672/
https://www.ncbi.nlm.nih.gov/pubmed/34521898
http://dx.doi.org/10.1038/s41598-021-97490-2