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The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites
Cruzipains are the main papain-like cysteine proteases of Trypanosoma cruzi, the protozoan parasite that causes Chagas disease. Encoded by a multigenic family, previous studies have estimated the presence of dozens of copies spread over multiple chromosomes in different parasite strains. Here, we de...
Autores principales: | Santos, Viviane Corrêa, Oliveira, Antonio Edson Rocha, Campos, Augusto César Broilo, Reis-Cunha, João Luís, Bartholomeu, Daniella Castanheira, Teixeira, Santuza Maria Ribeiro, Lima, Ana Paula C. A., Ferreira, Rafaela Salgado |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440672/ https://www.ncbi.nlm.nih.gov/pubmed/34521898 http://dx.doi.org/10.1038/s41598-021-97490-2 |
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