Duchenne muscular dystrophy cell culture models created by CRISPR/Cas9 gene editing and their application in drug screening 

Gene editing methods are an attractive therapeutic option for Duchenne muscular dystrophy, and they have an immediate application in the generation of research models. To generate myoblast cultures that could be useful in in vitro drug screening, we have optimised a CRISPR/Cas9 gene edition protocol...

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Detalles Bibliográficos
Autores principales: Soblechero-Martín, Patricia, Albiasu-Arteta, Edurne, Anton-Martinez, Aina, de la Puente-Ovejero, Laura, Garcia-Jimenez, Iker, González-Iglesias, Gabriela, Larrañaga-Aiestaran, Irene, López-Martínez, Andrea, Poyatos-García, Javier, Ruiz-Del-Yerro, Estíbaliz, Gonzalez, Federico, Arechavala-Gomeza, Virginia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440673/
https://www.ncbi.nlm.nih.gov/pubmed/34521928
http://dx.doi.org/10.1038/s41598-021-97730-5

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