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Single-cell RNA-Seq reveals transcriptional heterogeneity and immune subtypes associated with disease activity in human myasthenia gravis

Myasthenia gravis (MG) is a rare autoimmune disease. Although the impact of immune cell disorder in MG has been extensively studied, little is known about the transcriptomes of individual cells. Here, we assessed the transcriptional profiles of 39,243 cells by single-cell sequencing and identified 1...

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Detalles Bibliográficos
Autores principales: Jin, Wanlin, Yang, Qi, Peng, Yuyao, Yan, Chengkai, Li, Yi, Luo, Zhaohui, Xiao, Bo, Xu, Liqun, Yang, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440681/
https://www.ncbi.nlm.nih.gov/pubmed/34521820
http://dx.doi.org/10.1038/s41421-021-00314-w