Spermine-Related DNA Hypermethylation and Elevated Expression of Genes for Collagen Formation are Susceptible Factors for Chemotherapy-Induced Hand-Foot Syndrome in Chinese Colorectal Cancer Patients

Hand-foot syndrome (HFS) is a common capecitabine-based chemotherapy-related adverse event (CRAE) in patients with colorectal cancer (CRC). It is of great significance to comprehensively identify susceptible factors for HFS, and further to elucidate the biomolecular mechanism of HFS susceptibility....

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Detalles Bibliográficos
Autores principales: Li, Mingming, Chen, Jiani, Liu, Shaoqun, Sun, Xiaomeng, Xu, Huilin, Gao, Qianmin, Chen, Xintao, Xi, Chaowen, Huang, Doudou, Deng, Yi, Zhang, Feng, Gao, Shouhong, Qiu, Shi, Tao, Xia, Zhai, Jingwen, Wei, Hua, Yao, Houshan, Chen, Wansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440935/
https://www.ncbi.nlm.nih.gov/pubmed/34539419
http://dx.doi.org/10.3389/fphar.2021.746910

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