Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis

Pathological hallmarks of amyotrophic lateral sclerosis (ALS), including protein misfolding, are well established in oligodendrocytes. More recently, an RNA trafficking deficit of key myelin proteins has been suggested in oligodendrocytes in ALS but the extent to which this affects myelination and t...

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Detalles Bibliográficos
Autores principales: Barton, Samantha K., Gregory, Jenna M., Selvaraj, Bhuvaneish T., McDade, Karina, Henstridge, Christopher M., Spires-Jones, Tara L., James, Owen G., Mehta, Arpan R., Story, David, Burr, Karen, Magnani, Dario, Isaacs, Adrian M., Smith, Colin, Chandran, Siddharthan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440970/
https://www.ncbi.nlm.nih.gov/pubmed/34539336
http://dx.doi.org/10.3389/fnins.2021.705306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440970/
https://www.ncbi.nlm.nih.gov/pubmed/34539336
http://dx.doi.org/10.3389/fnins.2021.705306

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