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Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke

Vascular smooth muscle cells (VSMCs) have been widely recognized as key players in regulating blood-brain barrier (BBB) function, and their roles are unclear in ischemic stroke. Myosin phosphatase target subunit 1 (MYPT1) is essential for VSMC contraction and maintaining healthy vasculature. We gene...

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Detalles Bibliográficos
Autores principales: Meng, Hailan, Fan, Lizhen, Zhang, Cun-Jin, Zhu, Liwen, Liu, Pinyi, Chen, Jian, Bao, Xinyu, Pu, Zhijun, Zhu, Min-Sheng, Xu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441154/
https://www.ncbi.nlm.nih.gov/pubmed/34553133
http://dx.doi.org/10.1016/j.isci.2021.103047

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