YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling

Senescent astrocytes accumulate with aging and contribute to brain dysfunction and diseases such as Alzheimer's disease (AD), however, the mechanisms underlying the senescence of astrocytes during aging remain unclear. In the present study, we found that Yes‐associated Protein (YAP) was downreg...

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Detalles Bibliográficos
Autores principales: Xu, Xingxing, Shen, Xiya, Wang, Jiaojiao, Feng, Wenjin, Wang, Mianxian, Miao, Xuemeng, Wu, Qian, Wu, Lihao, Wang, Xiaoning, Ma, Yimin, Wu, Shuang, Bao, Xiaomei, Wang, Wei, Wang, Ying, Huang, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441453/
https://www.ncbi.nlm.nih.gov/pubmed/34415667
http://dx.doi.org/10.1111/acel.13465

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