Treatment of primary infertility in McCune-Albright syndrome: a case report of a successful in vitro fertilization cycle

OBJECTIVE: To report a case in which pregnancy and live birth were achieved in an infertile patient with McCune-Albright syndrome via in vitro fertilization (IVF). DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 29-year-old woman with McCune-Albright syndrome who presented with prim...

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Detalles Bibliográficos
Autores principales: Chung, Rebecca K., Mancuso, Abigail C., Kresowik, Jessica D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441555/
https://www.ncbi.nlm.nih.gov/pubmed/34553163
http://dx.doi.org/10.1016/j.xfre.2021.05.001
Descripción
Sumario:OBJECTIVE: To report a case in which pregnancy and live birth were achieved in an infertile patient with McCune-Albright syndrome via in vitro fertilization (IVF). DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 29-year-old woman with McCune-Albright syndrome who presented with primary infertility due to ovulatory dysfunction and bilateral tubal blockage. INTERVENTION(S): In vitro fertilization without unilateral oophorectomy. MAIN OUTCOME MEASURE(S): Live birth after IVF treatment. RESULT(S): Fresh IVF stimulation and bilateral oocyte retrieval yielded 12 oocytes and 4 top quality embryos. Fresh single embryo transfer did not result in pregnancy. Live birth occurred after the second frozen embryo transfer cycle. CONCLUSION(S): In vitro fertilization can lead to ongoing pregnancy in infertile patients with McCune-Albright syndrome without requiring unilateral oophorectomy.

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