Treatment of primary infertility in McCune-Albright syndrome: a case report of a successful in vitro fertilization cycle

OBJECTIVE: To report a case in which pregnancy and live birth were achieved in an infertile patient with McCune-Albright syndrome via in vitro fertilization (IVF). DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 29-year-old woman with McCune-Albright syndrome who presented with primary infertility due to ovulatory dysfunction and bilateral tubal blockage. INTERVENTION(S): In vitro fertilization without unilateral oophorectomy. MAIN OUTCOME MEASURE(S): Live birth after IVF treatment. RESULT(S): Fresh IVF stimulation and bilateral oocyte retrieval yielded 12 oocytes and 4 top quality embryos. Fresh single embryo transfer did not result in pregnancy. Live birth occurred after the second frozen embryo transfer cycle. CONCLUSION(S): In vitro fertilization can lead to ongoing pregnancy in infertile patients with McCune-Albright syndrome without requiring unilateral oophorectomy.