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Inferring gene regulatory networks from single-cell RNA-seq temporal snapshot data requires higher-order moments

Single-cell RNA sequencing (scRNA-seq) has become ubiquitous in biology. Recently, there has been a push for using scRNA-seq snapshot data to infer the underlying gene regulatory networks (GRNs) steering cellular function. To date, this aspiration remains unrealized due to technical and computationa...

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Detalles Bibliográficos
Autores principales: Raharinirina, N. Alexia, Peppert, Felix, von Kleist, Max, Schütte, Christof, Sunkara, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441581/
https://www.ncbi.nlm.nih.gov/pubmed/34553172
http://dx.doi.org/10.1016/j.patter.2021.100332