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Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy
INTRODUCTION:/AIMS: Patients with neuromuscular disorders (NMDs), including many elderly, immunosuppressed, and disabled individuals, may have been particularly affected during the coronavirus disease 2019 (COVID‐19) pandemic in Lombardy, a COVID‐19 high‐incidence area between February and May 2020....
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441795/ https://www.ncbi.nlm.nih.gov/pubmed/34296433 http://dx.doi.org/10.1002/mus.27378 |
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author | Gagliardi, Delia Costamagna, Gianluca Abati, Elena Mauri, Eleonora Brusa, Roberta Scudeller, Luigia Andreoli, Luca Citterio, Gaia Piccin, Eleonora Magri, Francesca Meneri, Megi Velardo, Daniele Sciacco, Monica Bresolin, Nereo Corti, Stefania Comi, Giacomo Pietro |
author_facet | Gagliardi, Delia Costamagna, Gianluca Abati, Elena Mauri, Eleonora Brusa, Roberta Scudeller, Luigia Andreoli, Luca Citterio, Gaia Piccin, Eleonora Magri, Francesca Meneri, Megi Velardo, Daniele Sciacco, Monica Bresolin, Nereo Corti, Stefania Comi, Giacomo Pietro |
author_sort | Gagliardi, Delia |
collection | PubMed |
description | INTRODUCTION:/AIMS: Patients with neuromuscular disorders (NMDs), including many elderly, immunosuppressed, and disabled individuals, may have been particularly affected during the coronavirus disease 2019 (COVID‐19) pandemic in Lombardy, a COVID‐19 high‐incidence area between February and May 2020. We aimed to evaluate the effects of the COVID‐19 pandemic on the quality of life (QoL) and perceived disease burden of this group of patients. METHODS: We conducted a cross‐sectional phone‐based survey study between June 1 and June 14, 2020, on a sample of 240 NMD patients followed at our clinic in Milan, Italy. We asked about perceived NMD burden and QoL before and during the COVID‐19 pandemic. We collected responses on access to outpatient care and ancillary services. We investigated the presence of symptoms suggestive of COVID‐19 infection and confirmed cases. RESULTS: We collected 205 responses: 53 patients (25.9%) reported a subjective worsening of the underlying NMD. QoL measures showed a significant worsening between pre and pandemic time frames (odds ratio, 2.14 95%; confidence interval, 1.82–2.51). Outpatient visits were postponed in more than half of cases (57.1%), with 104 patients (50.7%) experiencing a cancellation of scheduled diagnostic tests. 79 patients (38.5%) reported at least one symptom attributable to COVID‐19 infection. Among the 10 patients tested with nasopharyngeal swabs, 6 tested positive and 3 died from respiratory failure, including 2 patients on corticosteroid/ immunosuppressive therapy. DISCUSSION: The COVID‐19 pandemic affected QoL and limited access to outpatient care and ancillary services of NMD patients in Lombardy between February and May 2020. |
format | Online Article Text |
id | pubmed-8441795 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84417952021-09-15 Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy Gagliardi, Delia Costamagna, Gianluca Abati, Elena Mauri, Eleonora Brusa, Roberta Scudeller, Luigia Andreoli, Luca Citterio, Gaia Piccin, Eleonora Magri, Francesca Meneri, Megi Velardo, Daniele Sciacco, Monica Bresolin, Nereo Corti, Stefania Comi, Giacomo Pietro Muscle Nerve Clinical Research Articles INTRODUCTION:/AIMS: Patients with neuromuscular disorders (NMDs), including many elderly, immunosuppressed, and disabled individuals, may have been particularly affected during the coronavirus disease 2019 (COVID‐19) pandemic in Lombardy, a COVID‐19 high‐incidence area between February and May 2020. We aimed to evaluate the effects of the COVID‐19 pandemic on the quality of life (QoL) and perceived disease burden of this group of patients. METHODS: We conducted a cross‐sectional phone‐based survey study between June 1 and June 14, 2020, on a sample of 240 NMD patients followed at our clinic in Milan, Italy. We asked about perceived NMD burden and QoL before and during the COVID‐19 pandemic. We collected responses on access to outpatient care and ancillary services. We investigated the presence of symptoms suggestive of COVID‐19 infection and confirmed cases. RESULTS: We collected 205 responses: 53 patients (25.9%) reported a subjective worsening of the underlying NMD. QoL measures showed a significant worsening between pre and pandemic time frames (odds ratio, 2.14 95%; confidence interval, 1.82–2.51). Outpatient visits were postponed in more than half of cases (57.1%), with 104 patients (50.7%) experiencing a cancellation of scheduled diagnostic tests. 79 patients (38.5%) reported at least one symptom attributable to COVID‐19 infection. Among the 10 patients tested with nasopharyngeal swabs, 6 tested positive and 3 died from respiratory failure, including 2 patients on corticosteroid/ immunosuppressive therapy. DISCUSSION: The COVID‐19 pandemic affected QoL and limited access to outpatient care and ancillary services of NMD patients in Lombardy between February and May 2020. John Wiley & Sons, Inc. 2021-08-03 2021-10 /pmc/articles/PMC8441795/ /pubmed/34296433 http://dx.doi.org/10.1002/mus.27378 Text en © 2021 The Authors. Muscle & Nerve published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Clinical Research Articles Gagliardi, Delia Costamagna, Gianluca Abati, Elena Mauri, Eleonora Brusa, Roberta Scudeller, Luigia Andreoli, Luca Citterio, Gaia Piccin, Eleonora Magri, Francesca Meneri, Megi Velardo, Daniele Sciacco, Monica Bresolin, Nereo Corti, Stefania Comi, Giacomo Pietro Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy |
title | Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy |
title_full | Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy |
title_fullStr | Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy |
title_full_unstemmed | Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy |
title_short | Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy |
title_sort | impact of covid‐19 on the quality of life of patients with neuromuscular disorders in the lombardy area, italy |
topic | Clinical Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441795/ https://www.ncbi.nlm.nih.gov/pubmed/34296433 http://dx.doi.org/10.1002/mus.27378 |
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