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Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy

INTRODUCTION:/AIMS: Patients with neuromuscular disorders (NMDs), including many elderly, immunosuppressed, and disabled individuals, may have been particularly affected during the coronavirus disease 2019 (COVID‐19) pandemic in Lombardy, a COVID‐19 high‐incidence area between February and May 2020....

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Autores principales: Gagliardi, Delia, Costamagna, Gianluca, Abati, Elena, Mauri, Eleonora, Brusa, Roberta, Scudeller, Luigia, Andreoli, Luca, Citterio, Gaia, Piccin, Eleonora, Magri, Francesca, Meneri, Megi, Velardo, Daniele, Sciacco, Monica, Bresolin, Nereo, Corti, Stefania, Comi, Giacomo Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441795/
https://www.ncbi.nlm.nih.gov/pubmed/34296433
http://dx.doi.org/10.1002/mus.27378
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author Gagliardi, Delia
Costamagna, Gianluca
Abati, Elena
Mauri, Eleonora
Brusa, Roberta
Scudeller, Luigia
Andreoli, Luca
Citterio, Gaia
Piccin, Eleonora
Magri, Francesca
Meneri, Megi
Velardo, Daniele
Sciacco, Monica
Bresolin, Nereo
Corti, Stefania
Comi, Giacomo Pietro
author_facet Gagliardi, Delia
Costamagna, Gianluca
Abati, Elena
Mauri, Eleonora
Brusa, Roberta
Scudeller, Luigia
Andreoli, Luca
Citterio, Gaia
Piccin, Eleonora
Magri, Francesca
Meneri, Megi
Velardo, Daniele
Sciacco, Monica
Bresolin, Nereo
Corti, Stefania
Comi, Giacomo Pietro
author_sort Gagliardi, Delia
collection PubMed
description INTRODUCTION:/AIMS: Patients with neuromuscular disorders (NMDs), including many elderly, immunosuppressed, and disabled individuals, may have been particularly affected during the coronavirus disease 2019 (COVID‐19) pandemic in Lombardy, a COVID‐19 high‐incidence area between February and May 2020. We aimed to evaluate the effects of the COVID‐19 pandemic on the quality of life (QoL) and perceived disease burden of this group of patients. METHODS: We conducted a cross‐sectional phone‐based survey study between June 1 and June 14, 2020, on a sample of 240 NMD patients followed at our clinic in Milan, Italy. We asked about perceived NMD burden and QoL before and during the COVID‐19 pandemic. We collected responses on access to outpatient care and ancillary services. We investigated the presence of symptoms suggestive of COVID‐19 infection and confirmed cases. RESULTS: We collected 205 responses: 53 patients (25.9%) reported a subjective worsening of the underlying NMD. QoL measures showed a significant worsening between pre and pandemic time frames (odds ratio, 2.14 95%; confidence interval, 1.82–2.51). Outpatient visits were postponed in more than half of cases (57.1%), with 104 patients (50.7%) experiencing a cancellation of scheduled diagnostic tests. 79 patients (38.5%) reported at least one symptom attributable to COVID‐19 infection. Among the 10 patients tested with nasopharyngeal swabs, 6 tested positive and 3 died from respiratory failure, including 2 patients on corticosteroid/ immunosuppressive therapy. DISCUSSION: The COVID‐19 pandemic affected QoL and limited access to outpatient care and ancillary services of NMD patients in Lombardy between February and May 2020.
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spelling pubmed-84417952021-09-15 Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy Gagliardi, Delia Costamagna, Gianluca Abati, Elena Mauri, Eleonora Brusa, Roberta Scudeller, Luigia Andreoli, Luca Citterio, Gaia Piccin, Eleonora Magri, Francesca Meneri, Megi Velardo, Daniele Sciacco, Monica Bresolin, Nereo Corti, Stefania Comi, Giacomo Pietro Muscle Nerve Clinical Research Articles INTRODUCTION:/AIMS: Patients with neuromuscular disorders (NMDs), including many elderly, immunosuppressed, and disabled individuals, may have been particularly affected during the coronavirus disease 2019 (COVID‐19) pandemic in Lombardy, a COVID‐19 high‐incidence area between February and May 2020. We aimed to evaluate the effects of the COVID‐19 pandemic on the quality of life (QoL) and perceived disease burden of this group of patients. METHODS: We conducted a cross‐sectional phone‐based survey study between June 1 and June 14, 2020, on a sample of 240 NMD patients followed at our clinic in Milan, Italy. We asked about perceived NMD burden and QoL before and during the COVID‐19 pandemic. We collected responses on access to outpatient care and ancillary services. We investigated the presence of symptoms suggestive of COVID‐19 infection and confirmed cases. RESULTS: We collected 205 responses: 53 patients (25.9%) reported a subjective worsening of the underlying NMD. QoL measures showed a significant worsening between pre and pandemic time frames (odds ratio, 2.14 95%; confidence interval, 1.82–2.51). Outpatient visits were postponed in more than half of cases (57.1%), with 104 patients (50.7%) experiencing a cancellation of scheduled diagnostic tests. 79 patients (38.5%) reported at least one symptom attributable to COVID‐19 infection. Among the 10 patients tested with nasopharyngeal swabs, 6 tested positive and 3 died from respiratory failure, including 2 patients on corticosteroid/ immunosuppressive therapy. DISCUSSION: The COVID‐19 pandemic affected QoL and limited access to outpatient care and ancillary services of NMD patients in Lombardy between February and May 2020. John Wiley & Sons, Inc. 2021-08-03 2021-10 /pmc/articles/PMC8441795/ /pubmed/34296433 http://dx.doi.org/10.1002/mus.27378 Text en © 2021 The Authors. Muscle & Nerve published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Clinical Research Articles
Gagliardi, Delia
Costamagna, Gianluca
Abati, Elena
Mauri, Eleonora
Brusa, Roberta
Scudeller, Luigia
Andreoli, Luca
Citterio, Gaia
Piccin, Eleonora
Magri, Francesca
Meneri, Megi
Velardo, Daniele
Sciacco, Monica
Bresolin, Nereo
Corti, Stefania
Comi, Giacomo Pietro
Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy
title Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy
title_full Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy
title_fullStr Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy
title_full_unstemmed Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy
title_short Impact of COVID‐19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy
title_sort impact of covid‐19 on the quality of life of patients with neuromuscular disorders in the lombardy area, italy
topic Clinical Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441795/
https://www.ncbi.nlm.nih.gov/pubmed/34296433
http://dx.doi.org/10.1002/mus.27378
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