Upregulation of RIP3 promotes necroptosis via a ROS-dependent NF-κB pathway to induce chronic inflammation in HK-2 cells

Tubular atrophy/interstitial fibrosis (TA/IF) is a major cause of late allograft loss, and inflammation within areas of TA/IF is associated with adverse outcomes in kidney transplantation. However, there is currently no satisfactory method to suppress this inflammation to improve TA/IF. The present...

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Detalles Bibliográficos
Autores principales: Wei, Junjun, Chen, Liangliang, Wang, Duidui, Tang, Li, Xie, Zhenhua, Chen, Weifeng, Zhang, Shuwei, Weng, Guobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441977/
https://www.ncbi.nlm.nih.gov/pubmed/34498705
http://dx.doi.org/10.3892/mmr.2021.12423

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