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In Vitro Investigation of Thiolated Chitosan Derivatives as Mucoadhesive Coating Materials for Solid Lipid Nanoparticles

[Image: see text] In the present study, chitosan (CS) was thiolated by introducing l-cysteine via amide bond formation. Free thiol groups were protected with highly reactive 6-mercaptonicotinic acid (6-MNA) and less-reactive l-cysteine, respectively, via thiol/disulfide-exchange reactions. Unmodifie...

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Detalles Bibliográficos
Autores principales:	Wibel, Richard, Braun, Doris E., Hämmerle, Laurenz, Jörgensen, Arne M., Knoll, Patrick, Salvenmoser, Willi, Steinbring, Christian, Bernkop-Schnürch, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441978/ https://www.ncbi.nlm.nih.gov/pubmed/34459197 http://dx.doi.org/10.1021/acs.biomac.1c00776

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