Cargando…
Coherent Raman scattering imaging with a near-infrared achromatic metalens
Miniature handheld imaging devices and endoscopes based on coherent Raman scattering are promising for label-free in vivo optical diagnosis. Toward the development of these small-scale systems, a challenge arises from the design and fabrication of achromatic and high-end miniature optical components...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442248/ https://www.ncbi.nlm.nih.gov/pubmed/34553044 http://dx.doi.org/10.1063/5.0059874 |
_version_ | 1783752971858739200 |
---|---|
author | Lin, Peng Chen, Wei Ting Yousef, Kerolos M. A. Marchioni, Justin Zhu, Alexander Capasso, Federico Cheng, Ji-Xin |
author_facet | Lin, Peng Chen, Wei Ting Yousef, Kerolos M. A. Marchioni, Justin Zhu, Alexander Capasso, Federico Cheng, Ji-Xin |
author_sort | Lin, Peng |
collection | PubMed |
description | Miniature handheld imaging devices and endoscopes based on coherent Raman scattering are promising for label-free in vivo optical diagnosis. Toward the development of these small-scale systems, a challenge arises from the design and fabrication of achromatic and high-end miniature optical components for both pump and Stokes laser wavelengths. Here, we report a metasurface converting a low-cost plano–convex lens into a water-immersion, nearly diffraction-limited and achromatic lens. The metasurface comprising amorphous silicon nanopillars is designed in a way that all incident rays arrive at the focus with the same phase and group delay, leading to corrections of monochromatic and chromatic aberrations of the refractive lens, respectively. Compared to the case without the metasurface, the hybrid metasurface-refractive lens has higher Strehl ratios than the plano–convex lens and a tighter depth of focus. The hybrid metasurface-refractive lens is utilized in spectroscopic stimulated Raman scattering and coherent anti-Stokes Raman scattering imaging for the differentiation of two different polymer microbeads. Subsequently, the hybrid metalens is harnessed for volumetric coherent Raman scattering imaging of bead and tissue samples. Finally, we discuss possible approaches to integrate such hybrid metalens in a miniature scanning system for label-free coherent Raman scattering endoscopes. |
format | Online Article Text |
id | pubmed-8442248 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | AIP Publishing LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-84422482021-09-20 Coherent Raman scattering imaging with a near-infrared achromatic metalens Lin, Peng Chen, Wei Ting Yousef, Kerolos M. A. Marchioni, Justin Zhu, Alexander Capasso, Federico Cheng, Ji-Xin APL Photonics Articles Miniature handheld imaging devices and endoscopes based on coherent Raman scattering are promising for label-free in vivo optical diagnosis. Toward the development of these small-scale systems, a challenge arises from the design and fabrication of achromatic and high-end miniature optical components for both pump and Stokes laser wavelengths. Here, we report a metasurface converting a low-cost plano–convex lens into a water-immersion, nearly diffraction-limited and achromatic lens. The metasurface comprising amorphous silicon nanopillars is designed in a way that all incident rays arrive at the focus with the same phase and group delay, leading to corrections of monochromatic and chromatic aberrations of the refractive lens, respectively. Compared to the case without the metasurface, the hybrid metasurface-refractive lens has higher Strehl ratios than the plano–convex lens and a tighter depth of focus. The hybrid metasurface-refractive lens is utilized in spectroscopic stimulated Raman scattering and coherent anti-Stokes Raman scattering imaging for the differentiation of two different polymer microbeads. Subsequently, the hybrid metalens is harnessed for volumetric coherent Raman scattering imaging of bead and tissue samples. Finally, we discuss possible approaches to integrate such hybrid metalens in a miniature scanning system for label-free coherent Raman scattering endoscopes. AIP Publishing LLC 2021-09-01 2021-09-14 /pmc/articles/PMC8442248/ /pubmed/34553044 http://dx.doi.org/10.1063/5.0059874 Text en © 2021 Author(s). https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license. (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Articles Lin, Peng Chen, Wei Ting Yousef, Kerolos M. A. Marchioni, Justin Zhu, Alexander Capasso, Federico Cheng, Ji-Xin Coherent Raman scattering imaging with a near-infrared achromatic metalens |
title | Coherent Raman scattering imaging with a near-infrared achromatic metalens |
title_full | Coherent Raman scattering imaging with a near-infrared achromatic metalens |
title_fullStr | Coherent Raman scattering imaging with a near-infrared achromatic metalens |
title_full_unstemmed | Coherent Raman scattering imaging with a near-infrared achromatic metalens |
title_short | Coherent Raman scattering imaging with a near-infrared achromatic metalens |
title_sort | coherent raman scattering imaging with a near-infrared achromatic metalens |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442248/ https://www.ncbi.nlm.nih.gov/pubmed/34553044 http://dx.doi.org/10.1063/5.0059874 |
work_keys_str_mv | AT linpeng coherentramanscatteringimagingwithanearinfraredachromaticmetalens AT chenweiting coherentramanscatteringimagingwithanearinfraredachromaticmetalens AT yousefkerolosma coherentramanscatteringimagingwithanearinfraredachromaticmetalens AT marchionijustin coherentramanscatteringimagingwithanearinfraredachromaticmetalens AT zhualexander coherentramanscatteringimagingwithanearinfraredachromaticmetalens AT capassofederico coherentramanscatteringimagingwithanearinfraredachromaticmetalens AT chengjixin coherentramanscatteringimagingwithanearinfraredachromaticmetalens |