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MicroRNA-497 induced by Clonorchis sinensis enhances the TGF-β/Smad signaling pathway to promote hepatic fibrosis by targeting Smad7

BACKGROUND: Various stimuli, including Clonorchis sinensis infection, can cause liver fibrosis. Liver fibrosis is characterized by the activation of hepatic stellate cells (HSCs) with massive production of extracellular matrix (ECM). Our previous study showed that the TGF-β(1)-induced Smad signaling...

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Detalles Bibliográficos
Autores principales: Zhou, Qian-Yang, Yang, Hui-Min, Liu, Ji-Xin, Xu, Na, Li, Jing, Shen, Li-Ping, Zhang, Yu-Zhao, Koda, Stephane, Zhang, Bei-Bei, Yu, Qian, Chen, Jia-Xu, Zheng, Kui-Yang, Yan, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442346/
https://www.ncbi.nlm.nih.gov/pubmed/34521449
http://dx.doi.org/10.1186/s13071-021-04972-3