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High-frequency and activation of CD4(+)CD25(+) T cells maintain persistent immunotolerance induced by congenital ALV-J infection

Congenital avian leukosis virus subgroup J (ALV-J) infection can induce persistent immunotolerance in chicken, however, the underlying mechanism remains unclear. Here, we demonstrate that congenital ALV-J infection induces the production of high-frequency and activated CD4(+)CD25(+) Tregs that maint...

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Detalles Bibliográficos
Autores principales: He, Shuhai, Zheng, Gaoying, Zhou, Defang, Huang, Li, Dong, Jianguo, Cheng, Ziqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442411/
https://www.ncbi.nlm.nih.gov/pubmed/34526112
http://dx.doi.org/10.1186/s13567-021-00989-9