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Prominent gallbladder enlargement: Kawasaki disease or other congenital or acquired gallbladder disease? A case report
Kawasaki disease (KD) is a common systemic vasculitis in childhood that can result in damage to multiple body systems. However, prominent gallbladder (GB) enlargement in the acute stage is especially rare. A 5-year-old boy was admitted to the hospital with an 8-day history of a cervical mass, 7-day...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442496/ https://www.ncbi.nlm.nih.gov/pubmed/34496644 http://dx.doi.org/10.1177/03000605211041507 |
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author | Zhao, Liang Hua, Yimin Zhou, Kaiyu |
author_facet | Zhao, Liang Hua, Yimin Zhou, Kaiyu |
author_sort | Zhao, Liang |
collection | PubMed |
description | Kawasaki disease (KD) is a common systemic vasculitis in childhood that can result in damage to multiple body systems. However, prominent gallbladder (GB) enlargement in the acute stage is especially rare. A 5-year-old boy was admitted to the hospital with an 8-day history of a cervical mass, 7-day history of fever, and 5-day history of abdominal pain and rash. The child was diagnosed with KD. After treatment with high-dose intravenous immunoglobulin therapy (2 g/kg), all clinical manifestations were relieved except the abdominal pain. Enhanced computed tomography showed distinct enlargement of the GB, and a congenital choledochal cyst was strongly suspected. After high-dose glucocorticoid treatment, his obviously enlarged GB returned to normal size in the subacute phase. No abnormality was found during 2 years of follow-up. Prominent GB enlargement may emerge in the acute stage of KD. The enlarged GB can return to normal size within the subacute stage by standard treatment for KD. Proper diagnosis, thorough differential diagnosis, and active anti-inflammatory treatment of KD are crucial to avoid surgery. |
format | Online Article Text |
id | pubmed-8442496 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-84424962021-09-16 Prominent gallbladder enlargement: Kawasaki disease or other congenital or acquired gallbladder disease? A case report Zhao, Liang Hua, Yimin Zhou, Kaiyu J Int Med Res Case Reports Kawasaki disease (KD) is a common systemic vasculitis in childhood that can result in damage to multiple body systems. However, prominent gallbladder (GB) enlargement in the acute stage is especially rare. A 5-year-old boy was admitted to the hospital with an 8-day history of a cervical mass, 7-day history of fever, and 5-day history of abdominal pain and rash. The child was diagnosed with KD. After treatment with high-dose intravenous immunoglobulin therapy (2 g/kg), all clinical manifestations were relieved except the abdominal pain. Enhanced computed tomography showed distinct enlargement of the GB, and a congenital choledochal cyst was strongly suspected. After high-dose glucocorticoid treatment, his obviously enlarged GB returned to normal size in the subacute phase. No abnormality was found during 2 years of follow-up. Prominent GB enlargement may emerge in the acute stage of KD. The enlarged GB can return to normal size within the subacute stage by standard treatment for KD. Proper diagnosis, thorough differential diagnosis, and active anti-inflammatory treatment of KD are crucial to avoid surgery. SAGE Publications 2021-09-08 /pmc/articles/PMC8442496/ /pubmed/34496644 http://dx.doi.org/10.1177/03000605211041507 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Reports Zhao, Liang Hua, Yimin Zhou, Kaiyu Prominent gallbladder enlargement: Kawasaki disease or other congenital or acquired gallbladder disease? A case report |
title | Prominent gallbladder enlargement: Kawasaki disease or other congenital or
acquired gallbladder disease? A case report |
title_full | Prominent gallbladder enlargement: Kawasaki disease or other congenital or
acquired gallbladder disease? A case report |
title_fullStr | Prominent gallbladder enlargement: Kawasaki disease or other congenital or
acquired gallbladder disease? A case report |
title_full_unstemmed | Prominent gallbladder enlargement: Kawasaki disease or other congenital or
acquired gallbladder disease? A case report |
title_short | Prominent gallbladder enlargement: Kawasaki disease or other congenital or
acquired gallbladder disease? A case report |
title_sort | prominent gallbladder enlargement: kawasaki disease or other congenital or
acquired gallbladder disease? a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442496/ https://www.ncbi.nlm.nih.gov/pubmed/34496644 http://dx.doi.org/10.1177/03000605211041507 |
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