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Insulin/IGF-1 signaling and heat stress differentially regulate HSF1 activities in germline development
Germline development is sensitive to nutrient availability and environmental perturbation. Heat shock transcription factor 1 (HSF1), a key transcription factor driving the cellular heat shock response (HSR), is also involved in gametogenesis. The precise function of HSF1 (HSF-1 in C. elegans) and it...
Autores principales: | Edwards, Stacey L., Erdenebat, Purevsuren, Morphis, Allison C., Kumar, Lalit, Wang, Lai, Chamera, Tomasz, Georgescu, Constantin, Wren, Jonathan D., Li, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442575/ https://www.ncbi.nlm.nih.gov/pubmed/34469721 http://dx.doi.org/10.1016/j.celrep.2021.109623 |
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