Computational insights into the membrane fusion mechanism of SARS-CoV-2 at the cellular level

The membrane fusion mechanism of SARS-CoV-2 offers an attractive target for the development of small molecule antiviral inhibitors. Fusion involves an initial binding of the crown-like trimeric spike glycoproteins of SARS-CoV-2 to the receptor angiotensin II-converting enzyme 2 (ACE2) on the permiss...

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Detalles Bibliográficos
Autores principales: Wang, Jimin, Maschietto, Federica, Guberman-Pfeffer, Matthew J., Reiss, Krystle, Allen, Brandon, Xiong, Yong, Lolis, Elias, Batista, Victor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442599/
https://www.ncbi.nlm.nih.gov/pubmed/34540146
http://dx.doi.org/10.1016/j.csbj.2021.08.053

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