A universal bacteriophage T4 nanoparticle platform to design multiplex SARS-CoV-2 vaccine candidates by CRISPR engineering

A “universal” platform that can rapidly generate multiplex vaccine candidates is critically needed to control pandemics. Using the severe acute respiratory syndrome coronavirus 2 as a model, we have developed such a platform by CRISPR engineering of bacteriophage T4. A pipeline of vaccine candidates...

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Detalles Bibliográficos
Autores principales: Zhu, Jingen, Ananthaswamy, Neeti, Jain, Swati, Batra, Himanshu, Tang, Wei-Chun, Lewry, Douglass A., Richards, Michael L., David, Sunil A., Kilgore, Paul B., Sha, Jian, Drelich, Aleksandra, Tseng, Chien-Te K., Chopra, Ashok K., Rao, Venigalla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442874/
https://www.ncbi.nlm.nih.gov/pubmed/34516878
http://dx.doi.org/10.1126/sciadv.abh1547

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