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Microglia promote autoimmune inflammation via the noncanonical NF-κB pathway

Microglia have been implicated in neuroinflammatory diseases, including multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). We demonstrate that microglia mediate EAE disease progression via a mechanism relying on the noncanonical nuclear factor kB (NF-κB) pathway...

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Detalles Bibliográficos
Autores principales: Jie, Zuliang, Ko, Chun-Jung, Wang, Hui, Xie, Xiaoping, Li, Yanchuan, Gu, Meidi, Zhu, Lele, Yang, Jin-Young, Gao, Tianxiao, Ru, Wenjuan, Tang, Shao-Jun, Cheng, Xuhong, Sun, Shao-Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442891/
https://www.ncbi.nlm.nih.gov/pubmed/34516909
http://dx.doi.org/10.1126/sciadv.abh0609