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Switchable immune modulator for tumor-specific activation of anticancer immunity

Immune stimulatory antibodies and cytokines elicit potent antitumor immunity. However, the dose-limiting systemic toxicity greatly hinders their clinical applications. Here, we demonstrate a chemical approach, termed “switchable” immune modulator (Sw-IM), to limit the systemic exposure and therefore...

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Detalles Bibliográficos
Autores principales:	Zhao, Yu, Xie, Yu-Qing, Van Herck, Simon, Nassiri, Sina, Gao, Min, Guo, Yugang, Tang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442900/ https://www.ncbi.nlm.nih.gov/pubmed/34516776 http://dx.doi.org/10.1126/sciadv.abg7291

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